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Neurexin-2: An inhibitory neurexin that restricts excitatory synapse formation in the hippocampus
Neurexins are widely thought to promote synapse formation and to organize synapse properties. Here we found that in contrast to neurexin-1 and neurexin-3, neurexin-2 unexpectedly restricts synapse formation. In the hippocampus, constitutive or neuron-specific deletions of neurexin-2 nearly doubled t...
Autores principales: | Lin, Pei-Yi, Chen, Lulu Y., Jiang, Man, Trotter, Justin H., Seigneur, Erica, Südhof, Thomas C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821874/ https://www.ncbi.nlm.nih.gov/pubmed/36608123 http://dx.doi.org/10.1126/sciadv.add8856 |
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