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Synthesis of New Triazole-Based Thiosemicarbazone Derivatives as Anti-Alzheimer’s Disease Candidates: Evidence-Based In Vitro Study

Triazole-based thiosemicarbazone derivatives (6a–u) were synthesized then characterized by spectroscopic techniques, such as 1HNMR and 13CNMR and HRMS (ESI). Newly synthesized derivatives were screened in vitro for inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (Bu...

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Detalles Bibliográficos
Autores principales: Rahim, Fazal, Ullah, Hayat, Taha, Muhammad, Hussain, Rafaqat, Sarfraz, Maliha, Iqbal, Rashid, Iqbal, Naveed, Khan, Shoaib, Ali Shah, Syed Adnan, Albalawi, Marzough Aziz, Abdelaziz, Mahmoud A., Alatawi, Fatema Suliman, Alasmari, Abdulrahman, Sakran, Mohamed I., Zidan, Nahla, Jafri, Ibrahim, Khan, Khalid Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821906/
https://www.ncbi.nlm.nih.gov/pubmed/36615218
http://dx.doi.org/10.3390/molecules28010021