Synthesis and Antiprotozoal Activity of Azabicyclo-Nonane Pyrimidine Hybrids

2,4-Diaminopyrimidines and (dialkylamino)azabicyclo-nonanes possess activity against protozoan parasites. A series of fused hybrids were synthesized and tested in vitro against pathogens of malaria tropica and sleeping sickness. The activities and selectivities of compounds strongly depended on the...

Descripción completa

Detalles Bibliográficos
Autores principales: Hinteregger, Clemens, Dolensky, Johanna, Seebacher, Werner, Saf, Robert, Mäser, Pascal, Kaiser, Marcel, Weis, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821907/
https://www.ncbi.nlm.nih.gov/pubmed/36615504
http://dx.doi.org/10.3390/molecules28010307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821907/
https://www.ncbi.nlm.nih.gov/pubmed/36615504
http://dx.doi.org/10.3390/molecules28010307

Ejemplares similares