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8–17 DNAzyme Silencing Gene Expression in Cells via Cleavage and Antisense

Gene silencing is an important biological strategy for studying gene functions, exploring disease mechanisms and developing therapeutics. 8–17 DNAzyme is of great potential for gene silencing, due to its higher RNA-cleaving activity. However, it is not generally used in practice, due to its divalent...

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Detalles Bibliográficos
Autores principales: Zhou, Zhongchun, Sun, Wen, Huang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821912/
https://www.ncbi.nlm.nih.gov/pubmed/36615479
http://dx.doi.org/10.3390/molecules28010286