Cargando…

Single-cell profiling identifies ACE(+) granuloma macrophages as a nonpermissive niche for intracellular bacteria during persistent Salmonella infection

Macrophages mediate key antimicrobial responses against intracellular bacterial pathogens, such as Salmonella enterica. Yet, they can also act as a permissive niche for these pathogens to persist in infected tissues within granulomas, which are immunological structures composed of macrophages and ot...

Descripción completa

Detalles Bibliográficos
Autores principales: Pham, Trung H. M., Xue, Yuan, Brewer, Susan M., Bernstein, Kenneth E., Quake, Stephen R., Monack, Denise M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821941/
https://www.ncbi.nlm.nih.gov/pubmed/36608122
http://dx.doi.org/10.1126/sciadv.add4333