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Single-cell profiling identifies ACE(+) granuloma macrophages as a nonpermissive niche for intracellular bacteria during persistent Salmonella infection
Macrophages mediate key antimicrobial responses against intracellular bacterial pathogens, such as Salmonella enterica. Yet, they can also act as a permissive niche for these pathogens to persist in infected tissues within granulomas, which are immunological structures composed of macrophages and ot...
Autores principales: | Pham, Trung H. M., Xue, Yuan, Brewer, Susan M., Bernstein, Kenneth E., Quake, Stephen R., Monack, Denise M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821941/ https://www.ncbi.nlm.nih.gov/pubmed/36608122 http://dx.doi.org/10.1126/sciadv.add4333 |
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