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Synthetic Analogs of Marine Alkaloid Aplysinopsin Suppress Anti-Apoptotic Protein BCL2 in Prostate Cancer

Aplysinopsins are a class of indole alkaloids that possess various pharmacological activities. Although their action has been studied in regard to many diseases, their effect on prostate cancer has not yet been examined. Therefore, we synthesized a new series of aplysinopsin analogs and investigated...

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Detalles Bibliográficos
Autores principales: El-Sawy, Eslam R., El-Shahid, Zeinab A., Soliman, Ahmed A. F., Nassrallah, Amr, Abdelwahab, Ahmed B., Kirsch, Gilbert, Abdelmegeed, Heba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821956/
https://www.ncbi.nlm.nih.gov/pubmed/36615305
http://dx.doi.org/10.3390/molecules28010109