Virtual Screening, Synthesis, and Biological Evaluation of Some Carbohydrazide Derivatives as Potential DPP-IV Inhibitors

Dipeptidyl peptidase-4 (DPP-IV) inhibitors are known as safe and well-tolerated antidiabetic medicine. Therefore, the aim of the present work was to synthesize some carbohydrazide derivatives (1a–5d) as DPP-IV inhibitors. In addition, this work involves simulations using molecular docking, ADMET ana...

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Detalles Bibliográficos
Autores principales: Jadhav, Prerana B., Jadhav, Shailaja B., Zehravi, Mehrukh, Mubarak, Mohammad S., Islam, Fahadul, Jeandet, Philippe, Khan, Sharuk L., Hossain, Nazmul, Rashid, Salma, Ming, Long Chiau, Sarker, Md. Moklesur Rahman, Azlina, Mohd Fahami Nur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822036/
https://www.ncbi.nlm.nih.gov/pubmed/36615348
http://dx.doi.org/10.3390/molecules28010149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822036/
https://www.ncbi.nlm.nih.gov/pubmed/36615348
http://dx.doi.org/10.3390/molecules28010149

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