Straightforward Access to a New Class of Dual DYRK1A/CLK1 Inhibitors Possessing a Simple Dihydroquinoline Core

The DYRK (Dual-specificity tyrosine phosphorylation-regulated kinase) family of protein kinases is involved in the pathogenesis of several neurodegenerative diseases. Among them, the DYRK1A protein kinase is thought to be implicated in Alzheimer’s disease (AD) and Down syndrome, and as such, has eme...

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Detalles Bibliográficos
Autores principales: Ţînţaş, Mihaela-Liliana, Peauger, Ludovic, Alix, Florent, Papamicaël, Cyril, Besson, Thierry, Sopková-de Oliveira Santos, Jana, Gembus, Vincent, Levacher, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822041/
https://www.ncbi.nlm.nih.gov/pubmed/36615235
http://dx.doi.org/10.3390/molecules28010036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822041/
https://www.ncbi.nlm.nih.gov/pubmed/36615235
http://dx.doi.org/10.3390/molecules28010036

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