A Study on the Chemistry and Biological Activity of 26-Sulfur Analogs of Diosgenin: Synthesis of 26-Thiodiosgenin S-Mono- and Dioxides, and Their Alkyl Derivatives

A chemoselective procedure for MCPBA oxidation of 26-thiodiosgenin to corresponding sulfoxides and sulfone was elaborated. An unusual equilibration of sulfoxides in solution was observed. Moreover, α-alkylation of sulfoxide and sulfone was investigated. Finally, the biological activity of obtained c...

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Detalles Bibliográficos
Autores principales: Tomkiel, Aneta M., Czajkowska-Szczykowska, Dorota, Olchowik-Grabarek, Ewa, Rárová, Lucie, Sękowski, Szymon, Morzycki, Jacek W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822051/
https://www.ncbi.nlm.nih.gov/pubmed/36615383
http://dx.doi.org/10.3390/molecules28010189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822051/
https://www.ncbi.nlm.nih.gov/pubmed/36615383
http://dx.doi.org/10.3390/molecules28010189

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