Medicinal Chemistry of Anti-HIV-1 Latency Chemotherapeutics: Biotargets, Binding Modes and Structure-Activity Relationship Investigation

The existence of latent viral reservoirs (LVRs), also called latent cells, has long been an acknowledged stubborn hurdle for effective treatment of HIV-1/AIDS. This stable and heterogeneous reservoir, which mainly exists in resting memory CD4(+) T cells, is not only resistant to highly active antire...

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Detalles Bibliográficos
Autores principales: Wang, Yan-Kai, Wei, Long, Hu, Wei, Yu, Pei-Xia, Li, Zhong, Yu, Hai-Peng, Li, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822059/
https://www.ncbi.nlm.nih.gov/pubmed/36615199
http://dx.doi.org/10.3390/molecules28010003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822059/
https://www.ncbi.nlm.nih.gov/pubmed/36615199
http://dx.doi.org/10.3390/molecules28010003

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