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Safeguarding Drosophila female germ cell identity depends on an H3K9me3 mini domain guided by a ZAD zinc finger protein

H3K9me3-based gene silencing is a conserved strategy for securing cell fate, but the mechanisms controlling lineage-specific installation of this epigenetic mark remain unclear. In Drosophila, H3K9 methylation plays an essential role in securing female germ cell fate by silencing lineage inappropria...

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Detalles Bibliográficos
Autores principales: Shapiro-Kulnane, Laura, Selengut, Micah, Salz, Helen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822104/
https://www.ncbi.nlm.nih.gov/pubmed/36548300
http://dx.doi.org/10.1371/journal.pgen.1010568