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Chemoselective Synthesis of Mannich Adducts from 1,4-Naphthoquinones and Profile as Autophagic Inducers in Oral Squamous Cell Carcinoma

Oral squamous cell carcinoma (OSCC) is a worldwide public health problem, accounting for approximately 90% of all oral cancers, and is the eighth most common cancer in men. Cisplatin and carboplatin are the main chemotherapy drugs used in the clinic. However, in addition to their serious side effect...

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Detalles Bibliográficos
Autores principales: Borges, Amanda A., de Souza, Michele P., da Fonseca, Anna Carolina C., Wermelinger, Guilherme F., Ribeiro, Ruan C. B., Amaral, Adriane A. P., de Carvalho, Cláudio José C., Abreu, Lucas S., de Queiroz, Lucas Nicolau, de Almeida, Elan C. P., Rabelo, Vitor W., Abreu, Paula A., Pontes, Bruno, Ferreira, Vitor F., da Silva, Fernando de C., Forezi, Luana da S. M., Robbs, Bruno K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822194/
https://www.ncbi.nlm.nih.gov/pubmed/36615502
http://dx.doi.org/10.3390/molecules28010309