Synthesis and In Vitro Comparison of DOTA, NODAGA and 15-5 Macrocycles as Chelators for the (64)Cu-Labelling of Immunoconjugates

The development of (64)Cu-based immuno-PET radiotracers requires the use of copper-specific bifunctional chelators (BFCs) that contain functional groups allowing both convenient bioconjugation and stable copper complexes to limit in vivo bioreduction, transmetallation and/or transchelation. The exce...

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Detalles Bibliográficos
Autores principales: Maisonial-Besset, Aurélie, Witkowski, Tiffany, Quintana, Mercedes, Besse, Sophie, Gaumet, Vincent, Cordonnier, Axel, Alliot, Cyrille, Vidal, Aurélien, Denevault-Sabourin, Caroline, Tarrit, Sébastien, Levesque, Sophie, Miot-Noirault, Elisabeth, Chezal, Jean-Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822305/
https://www.ncbi.nlm.nih.gov/pubmed/36615280
http://dx.doi.org/10.3390/molecules28010075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822305/
https://www.ncbi.nlm.nih.gov/pubmed/36615280
http://dx.doi.org/10.3390/molecules28010075

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