Cargando…

Molecular Mechanisms of Aggregation of Canine SOD1 E40K Amyloidogenic Mutant Protein

Canine degenerative myelopathy (DM) is a human amyotrophic lateral sclerosis (ALS)-like neurodegenerative disease. It is a unique, naturally occurring animal model of human ALS. Canine DM is associated with the aggregation of canine superoxide dismutase 1 (cSOD1), which is similar to human ALS. Almo...

Descripción completa

Detalles Bibliográficos
Autores principales: Wakayama, Kento, Kimura, Shintaro, Kobatake, Yui, Kamishina, Hiroaki, Nishii, Naohito, Takashima, Satoshi, Honda, Ryo, Kamatari, Yuji O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822309/
https://www.ncbi.nlm.nih.gov/pubmed/36615350
http://dx.doi.org/10.3390/molecules28010156