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Molecular Mechanisms of Aggregation of Canine SOD1 E40K Amyloidogenic Mutant Protein
Canine degenerative myelopathy (DM) is a human amyotrophic lateral sclerosis (ALS)-like neurodegenerative disease. It is a unique, naturally occurring animal model of human ALS. Canine DM is associated with the aggregation of canine superoxide dismutase 1 (cSOD1), which is similar to human ALS. Almo...
Autores principales: | Wakayama, Kento, Kimura, Shintaro, Kobatake, Yui, Kamishina, Hiroaki, Nishii, Naohito, Takashima, Satoshi, Honda, Ryo, Kamatari, Yuji O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822309/ https://www.ncbi.nlm.nih.gov/pubmed/36615350 http://dx.doi.org/10.3390/molecules28010156 |
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