Synthesis, Biological Evaluation, DNA Binding, and Molecular Docking of Hybrid 4,6-Dihydrazone Pyrimidine Derivatives as Antitumor Agents

In the present paper, on the basis of molecular hybridization, a series of 4,6-dihydrazone pyrimidine derivatives containing the pyridine moiety were synthesized, structurally characterized, and evaluated in vitro for their antitumor activity. According to the results, all the tested compounds demon...

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Detalles Bibliográficos
Autores principales: Lan, Hairong, Song, Junying, Yuan, Juan, Xing, Aiping, Zeng, Dai, Hao, Yating, Zhang, Zhenqiang, Feng, Shuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822369/
https://www.ncbi.nlm.nih.gov/pubmed/36615380
http://dx.doi.org/10.3390/molecules28010187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822369/
https://www.ncbi.nlm.nih.gov/pubmed/36615380
http://dx.doi.org/10.3390/molecules28010187

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