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Synthesis, Biological Evaluation, DNA Binding, and Molecular Docking of Hybrid 4,6-Dihydrazone Pyrimidine Derivatives as Antitumor Agents

In the present paper, on the basis of molecular hybridization, a series of 4,6-dihydrazone pyrimidine derivatives containing the pyridine moiety were synthesized, structurally characterized, and evaluated in vitro for their antitumor activity. According to the results, all the tested compounds demon...

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Detalles Bibliográficos
Autores principales:	Lan, Hairong, Song, Junying, Yuan, Juan, Xing, Aiping, Zeng, Dai, Hao, Yating, Zhang, Zhenqiang, Feng, Shuying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822369/ https://www.ncbi.nlm.nih.gov/pubmed/36615380 http://dx.doi.org/10.3390/molecules28010187

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