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Synthesis of Some Mono- and Disaccharide-Grafting Phthalazine Derivatives and Some New Se-Nucleoside Analogues: Antibacterial Properties, Quantum Chemical Calculations, and Cytotoxicity

A highly efficient and versatile synthetic approach for the synthesis of 4-(pyren-1-ylmethyl)-1-(d-glycosyloxy) phthalazine nucleosides 11a,b, 13, β-S-nucleosides 16, 18, 20, and acyclo C-nucleosides 23a,b, 24, 25 and 27a–f was described and fully characterized. Furthermore, a series of desired new...

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Detalles Bibliográficos
Autores principales: El-Shamy, I. E., Hleli, E., Alsheikh, A. A., Yawer, M. A., El-Hashash, M. A., Dybal, J., Abdel-Mohsen, A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822378/
https://www.ncbi.nlm.nih.gov/pubmed/36615511
http://dx.doi.org/10.3390/molecules28010317