Medicarpin and Homopterocarpin Isolated from Canavalia lineata as Potent and Competitive Reversible Inhibitors of Human Monoamine Oxidase-B

Thirteen compounds were isolated from the Canavalia lineata pods and their inhibitory activities against human monoamine oxidase-A (hMAO-A) and -B (hMAO-B) were evaluated. Among them, compounds 8 (medicarpin) and 13 (homopterocarpin) showed potent inhibitory activity against hMAO-B (IC(50) = 0.45 an...

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Detalles Bibliográficos
Autores principales: Oh, Jong Min, Jang, Hyun-Jae, Kang, Myung-Gyun, Mun, Seul-Ki, Park, Daeui, Hong, Su-Jin, Kim, Min Ha, Kim, Soo-Young, Yee, Sung-Tae, Kim, Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822396/
https://www.ncbi.nlm.nih.gov/pubmed/36615451
http://dx.doi.org/10.3390/molecules28010258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822396/
https://www.ncbi.nlm.nih.gov/pubmed/36615451
http://dx.doi.org/10.3390/molecules28010258

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