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Investigation on Hydrazonobenzenesulfonamides as Human Carbonic Anhydrase I, II, IX and XII Inhibitors

A small series of hydrazonobenzenesulfonamides was designed, synthesized and studied for their human carbonic anhydrase (hCA) inhibitory activity. The synthesized compounds were evaluated against hCA I, II, IX and XII isoforms using acetazolamide (AAZ) as the standard inhibitor. Various hydrazonosul...

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Detalles Bibliográficos
Autores principales: Moi, Davide, Vittorio, Serena, Angeli, Andrea, Balboni, Gianfranco, Supuran, Claudiu T., Onnis, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822402/
https://www.ncbi.nlm.nih.gov/pubmed/36615285
http://dx.doi.org/10.3390/molecules28010091