Design, Catalyst-Free Synthesis of New Novel α-Trifluoromethylated Tertiary Alcohols Bearing Coumarins as Potential Antifungal Agents

A new method for the synthesis of α-trifluoromethylated tertiary alcohols bearing coumarins is described. The reaction of 3-(trifluoroacetyl)coumarin and pyrrole provided the target compounds with high yields under catalyst-free, mild conditions. The crystal structure of compound 3fa was investigate...

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Detalles Bibliográficos
Autores principales: Jiang, Shengfei, Yang, Guoyu, Shi, Lijun, Fan, Liangxin, Pan, Zhenliang, Wang, Caixia, Chang, Xiaodan, Zhou, Bingyi, Xu, Meng, Wu, Lulu, Xu, Cuilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822406/
https://www.ncbi.nlm.nih.gov/pubmed/36615454
http://dx.doi.org/10.3390/molecules28010260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822406/
https://www.ncbi.nlm.nih.gov/pubmed/36615454
http://dx.doi.org/10.3390/molecules28010260

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