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C/EBPβ/AEP is age-dependently activated in Parkinson’s disease and mediates α-synuclein in the gut and brain

Parkinson’s disease (PD) is the most common neurodegenerative motor disorder, and its pathologic hallmarks include extensive dopaminergic neuronal degeneration in the Substantia nigra associated with Lewy bodies, predominantly consisting of phosphorylated and truncated α-Synuclein (α-Syn). Asparagin...

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Detalles Bibliográficos
Autores principales: Wang, Hualong, Chen, Guiqin, Ahn, Eun Hee, Xia, Yiyuan, Kang, Seong Su, Liu, Xia, Liu, Chang, Han, Ming-Hu, Chen, Shengdi, Ye, Keqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822984/
https://www.ncbi.nlm.nih.gov/pubmed/36609384
http://dx.doi.org/10.1038/s41531-022-00430-8