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Population Pharmacokinetic–Pharmacodynamic Modeling and Probability of Target Attainment Analysis of Rocuronium and Sugammadex in Children Undergoing Surgery

BACKGROUND AND OBJECTIVES: Probability of target attainment (PTA) curves are commonly used to support dose recommendations of antibiotics for different patient groups. In this study we propose PTA analysis to optimize sugammadex dosing in children. METHODS: This study involved data from an observati...

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Detalles Bibliográficos
Autores principales: Grześkowiak, Małgorzata, Bienert, Agnieszka, Wiczling, Paweł, Malec, Mirosław, Grzelak, Joanna, Jarosz, Konrad, Ber, Justyna, Książkiewicz, Michał, Rosada-Kurasińska, Jowita, Grześkowiak, Edmund, Bartkowska-Śniatkowska, Alicja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823043/
https://www.ncbi.nlm.nih.gov/pubmed/36477706
http://dx.doi.org/10.1007/s13318-022-00809-1