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MR-DoC2: Bidirectional Causal Modeling with Instrumental Variables and Data from Relatives

Establishing causality is an essential step towards developing interventions for psychiatric disorders, substance use and many other conditions. While randomized controlled trials (RCTs) are considered the gold standard for causal inference, they are unethical in many scenarios. Mendelian randomizat...

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Detalles Bibliográficos
Autores principales: Castro-de-Araujo, Luis F. S., Singh, Madhurbain, Zhou, Yi, Vinh, Philip, Verhulst, Brad, Dolan, Conor V., Neale, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823046/
https://www.ncbi.nlm.nih.gov/pubmed/36322200
http://dx.doi.org/10.1007/s10519-022-10122-x