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Pharmacokinetic Interactions and Tolerability of Rosuvastatin and Ezetimibe: A Randomized, Phase 1, Crossover Study in Healthy Chinese Participants

BACKGROUND AND OBJECTIVE: The combination of rosuvastatin and ezetimibe has promising clinical benefits with a significant safety and tolerability profile. However, there is a lack of clinical data supporting the drug–drug interaction (DDI) in Chinese population. Thus, the aim of this study is to as...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Luan, Yingcai, Jia, Chuandong, Xie, Xin, Zhang, Zihao, Xie, Xiaochuan, Wang, Qian, Hu, Chanyan, Xie, Fang, Abdel-Moneim, Mohamed, Hovsepian, Lionel, Zhao, Zhihong, Yang, Na, Hou, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823065/
https://www.ncbi.nlm.nih.gov/pubmed/36437383
http://dx.doi.org/10.1007/s13318-022-00798-1