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Paclitaxel Regulates TRPA1 Function and Expression Through PKA and PKC

Paclitaxel (PTX) is a frequently used anticancer drug that causes peripheral neuropathy. Transient receptor potential ankyrin 1 (TRPA1), a plasma membrane calcium channel, has been associated with PTX toxicity and with other chemotherapy agents such as oxaliplatin and vincristine. However, the effec...

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Detalles Bibliográficos
Autores principales: Sánchez, Julio C., Muñoz, Laura V., Galindo-Márquez, María-Leonor, Valencia-Vásquez, Aníbal, García, Andrés M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823074/
https://www.ncbi.nlm.nih.gov/pubmed/36098890
http://dx.doi.org/10.1007/s11064-022-03748-0