Cargando…

EMC3 regulates mesenchymal cell survival via control of the mitotic spindle assembly

Eukaryotic cells transit through the cell cycle to produce two daughter cells. Dysregulation of the cell cycle leads to cell death or tumorigenesis. Herein, we found a subunit of the ER membrane complex, EMC3, as a key regulator of cell cycle. Conditional deletion of Emc3 in mouse embryonic mesoderm...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Xiaofang, Wei, Wei, Snowball, John M., Nakayasu, Ernesto S., Bell, Sheila M., Ansong, Charles, Lin, Xinhua, Whitsett, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823123/
https://www.ncbi.nlm.nih.gov/pubmed/36624844
http://dx.doi.org/10.1016/j.isci.2022.105667