Phosphatidylinositol (3,5)-bisphosphate machinery regulates neurite thickness through neuron-specific endosomal protein NSG1/NEEP21

Phosphatidylinositol (3,5)-bisphosphate [PtdIns(3,5)P(2)] is a critical signaling phospholipid involved in endolysosome homeostasis. It is synthesized by a protein complex composed of PIKfyve, Vac14, and Fig4. Defects in PtdIns(3,5)P(2) synthesis underlie a number of human neurological disorders, in...

Descripción completa

Detalles Bibliográficos
Autores principales: Qi, Lijuan, Sun, Chen, Sun, Shenqing, Li, Aiqing, Hu, Qiuming, Liu, Yaobo, Zhang, Yanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823133/
https://www.ncbi.nlm.nih.gov/pubmed/36493904
http://dx.doi.org/10.1016/j.jbc.2022.102775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823133/
https://www.ncbi.nlm.nih.gov/pubmed/36493904
http://dx.doi.org/10.1016/j.jbc.2022.102775

Ejemplares similares