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Surface electrostatics dictate RNA-binding protein CAPRIN1 condensate concentration and hydrodynamic properties

Biomolecular condensates concentrate proteins, nucleic acids, and small molecules and play an essential role in many biological processes. Their formation is tuned by a balance between energetically favorable and unfavorable contacts, with charge–charge interactions playing a central role in some sy...

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Detalles Bibliográficos
Autores principales: Toyama, Yuki, Rangadurai, Atul Kaushik, Forman-Kay, Julie D., Kay, Lewis E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823214/
https://www.ncbi.nlm.nih.gov/pubmed/36496075
http://dx.doi.org/10.1016/j.jbc.2022.102776