High-efficiency purification of divergent AAV serotypes using AAVX affinity chromatography

The adeno-associated viral vector (AAV) provides a safe and efficient gene therapy platform with several approved products that have marked therapeutic impact for patients. However, a major bottleneck in the development and commercialization of AAV remains the efficiency, cost, and scalability of AA...

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Detalles Bibliográficos
Autores principales: Florea, Michael, Nicolaou, Fotini, Pacouret, Simon, Zinn, Eric M., Sanmiguel, Julio, Andres-Mateos, Eva, Unzu, Carmen, Wagers, Amy J., Vandenberghe, Luk H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823220/
https://www.ncbi.nlm.nih.gov/pubmed/36654797
http://dx.doi.org/10.1016/j.omtm.2022.12.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823220/
https://www.ncbi.nlm.nih.gov/pubmed/36654797
http://dx.doi.org/10.1016/j.omtm.2022.12.009

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