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Reductive Deuteration of Acyl Chlorides for the Synthesis of α,α-Dideuterio Alcohols Using SmI(2) and D(2)O

The synthesis of α,α-dideuterio alcohols has been achieved via single electron transfer reductive deuteration of acyl chlorides using SmI(2) and D(2)O. This method is distinguished by its remarkable functional group tolerance and exquisite deuterium incorporation, which has also been applied to the...

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Detalles Bibliográficos
Autores principales: Li, Hengzhao, Hou, Yuxia, Peng, Mengqi, Wang, Lijun, Li, Junyu, Ning, Lei, Lai, Zemin, Li, Yixuan, An, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823311/
https://www.ncbi.nlm.nih.gov/pubmed/36615608
http://dx.doi.org/10.3390/molecules28010416