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Reductive Deuteration of Acyl Chlorides for the Synthesis of α,α-Dideuterio Alcohols Using SmI(2) and D(2)O
The synthesis of α,α-dideuterio alcohols has been achieved via single electron transfer reductive deuteration of acyl chlorides using SmI(2) and D(2)O. This method is distinguished by its remarkable functional group tolerance and exquisite deuterium incorporation, which has also been applied to the...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823311/ https://www.ncbi.nlm.nih.gov/pubmed/36615608 http://dx.doi.org/10.3390/molecules28010416 |