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Optimization of Gefitinib-Loaded Nanostructured Lipid Carrier as a Biomedical Tool in the Treatment of Metastatic Lung Cancer

Gefitinib (GEF) is utilized in clinical settings for the treatment of metastatic lung cancer. However, premature drug release from nanoparticles in vivo increases the exposure of systemic organs to GEF. Herein, nanostructured lipid carriers (NLC) were utilized not only to avoid premature drug releas...

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Detalles Bibliográficos
Autores principales: Sherif, Abdelrahman Y., Harisa, Gamaleldin I., Shahba, Ahmad A., Alanazi, Fars K., Qamar, Wajhul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823586/
https://www.ncbi.nlm.nih.gov/pubmed/36615641
http://dx.doi.org/10.3390/molecules28010448