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Enhancing the Antifungal Activity and Ophthalmic Transport of Fluconazole from PEGylated Polycaprolactone Loaded Nanoparticles

Fungal eye infections are caused mainly by an eye injury and can result in serious eye damage. Fluconazole (FLZ), a broad-spectrum antifungal agent, is a poorly soluble drug with a risk of hepatotoxicity. This work aimed to investigate the antifungal activity, ocular irritation, and transport of FLZ...

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Detalles Bibliográficos
Autores principales: Almehmady, Alshaimaa M., El-Say, Khalid M., Mubarak, Manal A., Alghamdi, Haneen A., Somali, Njood A., Sirwi, Alaa, Algarni, Rahmah, Ahmed, Tarek A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823753/
https://www.ncbi.nlm.nih.gov/pubmed/36616558
http://dx.doi.org/10.3390/polym15010209