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Synthesis of Methacryloylated Hydroxyethylcellulose and Development of Mucoadhesive Wafers for Buccal Drug Delivery

Non-ionic hydroxyethylcellulose (HEC) has limited mucoadhesive properties for application in transmucosal drug delivery. In this study, HEC was chemically modified by reaction with glycidyl methacrylate. This allowed introducing the methacryloyl groups to HEC structure to make it capable of forming...

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Detalles Bibliográficos
Autores principales: Buang, Fhataheya, Chatzifragkou, Afroditi, Amin, Mohd Cairul Iqbal Mohd, Khutoryanskiy, Vitaliy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823848/
https://www.ncbi.nlm.nih.gov/pubmed/36616443
http://dx.doi.org/10.3390/polym15010093