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Sigma-1 Receptor Activation Improves Oligodendrogenesis and Promotes White-Matter Integrity after Stroke in Mice with Diabetic Mellitus

Diabetes mellitus (DM) is a major risk factor for stroke and exacerbates white-matter damage in focal cerebral ischemia. Our previous study showed that the sigma-1 receptor agonist PRE084 ameliorates bilateral common-carotid-artery occlusion-induced brain damage in mice. However, whether this protec...

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Detalles Bibliográficos
Autores principales: Song, Wenjing, Yao, Yang, Zhang, Heling, Hao, Xin, Zhou, Liping, Song, Zhixiao, Wei, Tiantian, Chi, Tianyan, Liu, Peng, Ji, Xuefei, Zou, Libo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823930/
https://www.ncbi.nlm.nih.gov/pubmed/36615583
http://dx.doi.org/10.3390/molecules28010390