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Catalpol Attenuates Oxidative Stress and Inflammation via Mechanisms Involving Sirtuin-1 Activation and NF-κB Inhibition in Experimentally-Induced Chronic Kidney Disease

Chronic kidney disease (CKD) is a stealthy disease, and its development is linked to mechanisms including inflammation and oxidative stress. Catalpol (CAT), an iridoid glucoside from the root of Rehmannia glutinosa, is reported to manifest anti-inflammatory, antioxidant, antiapoptotic and antifibrot...

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Detalles Bibliográficos
Autores principales: Zaaba, Nur Elena, Al-Salam, Suhail, Beegam, Sumaya, Elzaki, Ozaz, Yasin, Javed, Nemmar, Abderrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824177/
https://www.ncbi.nlm.nih.gov/pubmed/36615896
http://dx.doi.org/10.3390/nu15010237