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A Comparison of Primary Human Hepatocytes and Hepatoma Cell Lines to Model the Effects of Fatty Acids, Fructose and Glucose on Liver Cell Lipid Accumulation

Non-alcoholic fatty liver disease (NAFLD) begins with lipid accumulation within hepatocytes, but the relative contributions of different macronutrients is still unclear. We investigated the impact of fatty acids, glucose and fructose on lipid accumulation in primary human hepatocytes (PHH) and three...

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Detalles Bibliográficos
Autores principales: Huggett, Zoë J., Smith, Alison, De Vivo, Nicola, Gomez, Dhanny, Jethwa, Preeti, Brameld, John M., Bennett, Andrew, Salter, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824391/
https://www.ncbi.nlm.nih.gov/pubmed/36615698
http://dx.doi.org/10.3390/nu15010040