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Vitamin D, Folic Acid and Vitamin B(12) Can Reverse Vitamin D Deficiency-Induced Learning and Memory Impairment by Altering 27-Hydroxycholesterol and S-Adenosylmethionine

The cholesterol-oxidized metabolite 27-hydroxycholesterol (27-OHC) is synthesized by CYP27A1, which is a key factor in vitamin D and oxysterol metabolism. Both vitamin D and 27-OHC are considered to play important roles in Alzheimer’s disease (AD). The study aims to research the effects of co-supple...

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Detalles Bibliográficos
Autores principales: Wang, Lijing, Zhou, Cui, Yu, Huiyan, Hao, Ling, Ju, Mengwei, Feng, Wenjing, Guo, Zhiting, Sun, Xuejing, Fan, Qiushi, Xiao, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824694/
https://www.ncbi.nlm.nih.gov/pubmed/36615790
http://dx.doi.org/10.3390/nu15010132