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Depletion of Zinc Causes Osteoblast Apoptosis with Elevation of Leptin Secretion and Phosphorylation of JAK2/STAT3

Zinc (Zn) has been reported to mediate leptin secretion, and thus leptin can be an important candidate molecule linking Zn with bone formation. The present study investigated whether zinc deficiency induces leptin secretion by activating a JAK2/STAT3 signaling pathway and leads to osteoblastic apopt...

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Detalles Bibliográficos
Autores principales: Lee, Jennifer K., Ha, Jung-Heun, Kim, Do-Kyun, Kwon, JaeHee, Cho, Young-Eun, Kwun, In-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824754/
https://www.ncbi.nlm.nih.gov/pubmed/36615735
http://dx.doi.org/10.3390/nu15010077