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The N6-methyladenosine METTL3 regulates tumorigenesis and glycolysis by mediating m6A methylation of the tumor suppressor LATS1 in breast cancer

BACKGROUND: Posttranscriptional modification of tumor-associated factors plays a pivotal role in breast cancer progression. However, the underlying mechanism remains unknown. M6A modifications in cancer cells are dynamic and reversible and have been found to impact tumor initiation and progression t...

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Detalles Bibliográficos
Autores principales: Xu, Youqin, Song, Mu, Hong, Ziyang, Chen, Wancheng, Zhang, Qianbing, Zhou, Jianlong, Yang, Chao, He, Zilong, Yu, Juanjuan, Peng, Xiaolin, Zhu, Qiuhong, Li, Shaotian, Ji, Kaiyuan, Liu, Minfeng, Zuo, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824909/
https://www.ncbi.nlm.nih.gov/pubmed/36609396
http://dx.doi.org/10.1186/s13046-022-02581-1