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The miR-15b-Smurf2-HSP27 axis promotes pulmonary fibrosis

BACKGROUND: Heat shock protein 27 (HSP27) is overexpressed during pulmonary fibrosis (PF) and exacerbates PF; however, the upregulation of HSP27 during PF and the therapeutic strategy of HSP27 inhibition is not well elucidated. METHODS: We have developed a mouse model simulating clinical stereotacti...

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Detalles Bibliográficos
Autores principales: Jeon, Seulgi, Jin, Hee, Kim, Jin-Mo, Hur, Youmin, Song, Eun Joo, Lee, Yoon-Jin, Na, Younghwa, Cho, Jaeho, Lee, Yun-Sil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824921/
https://www.ncbi.nlm.nih.gov/pubmed/36611161
http://dx.doi.org/10.1186/s12929-023-00896-5