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The miR-15b-Smurf2-HSP27 axis promotes pulmonary fibrosis
BACKGROUND: Heat shock protein 27 (HSP27) is overexpressed during pulmonary fibrosis (PF) and exacerbates PF; however, the upregulation of HSP27 during PF and the therapeutic strategy of HSP27 inhibition is not well elucidated. METHODS: We have developed a mouse model simulating clinical stereotacti...
Autores principales: | Jeon, Seulgi, Jin, Hee, Kim, Jin-Mo, Hur, Youmin, Song, Eun Joo, Lee, Yoon-Jin, Na, Younghwa, Cho, Jaeho, Lee, Yun-Sil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824921/ https://www.ncbi.nlm.nih.gov/pubmed/36611161 http://dx.doi.org/10.1186/s12929-023-00896-5 |
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