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Male-specific, replicable and functional roles of genetic variants and cerebral gray matter volumes in ADHD: a gene-wide association study across KTN1 and a region-wide functional validation across brain

Attention deficit hyperactivity disorder (ADHD) is associated with reduction of cortical and subcortical gray matter volumes (GMVs). The kinectin 1 gene (KTN1) has recently been reported to significantly regulate GMVs and ADHD risk. In this study, we aimed to identify sex-specific, replicable risk K...

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Detalles Bibliográficos
Autores principales: Luo, Xingguang, Lin, Xiandong, Ide, Jaime S., Luo, Xinqun, Zhang, Yong, Xu, Jianying, Wang, Leilei, Chen, Yu, Cheng, Wenhong, Zheng, Jianming, Wang, Zhiren, Yu, Ting, Taximaimaiti, Reyisha, Jing, Xiaozhong, Wang, Xiaoping, Cao, Yuping, Tan, Yunlong, Li, Chiang-Shan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824933/
https://www.ncbi.nlm.nih.gov/pubmed/36609385
http://dx.doi.org/10.1186/s13034-022-00536-0