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Splicing factor-mediated regulation patterns reveals biological characteristics and aid in predicting prognosis in acute myeloid leukemia

BACKGROUND: Alternative splicing (AS) of RNA is a fundamental biological process that shapes protein diversity. Many non-characteristic AS events are involved in the onset and development of acute myeloid leukemia (AML). Abnormal alterations in splicing factors (SFs), which regulate the onset of AS...

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Detalles Bibliográficos
Autores principales: Zhong, Fang-Min, Yao, Fang-Yi, Liu, Jing, Li, Mei-Yong, Jiang, Jun-Yao, Cheng, Ying, Xu, Shuai, Li, Shu-Qi, Zhang, Nan, Huang, Bo, Wang, Xiao-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824960/
https://www.ncbi.nlm.nih.gov/pubmed/36611187
http://dx.doi.org/10.1186/s12967-022-03868-9