Elamipretide alleviates pyroptosis in traumatically injured spinal cord by inhibiting cPLA2-induced lysosomal membrane permeabilization

Spinal cord injury (SCI) is a devastating injury that may result in permanent motor impairment. The active ingredients of medications are unable to reach the affected area due to the blood‒brain barrier. Elamipretide (SS-31) is a new and innovative aromatic cationic peptide. Because of its alternati...

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Detalles Bibliográficos
Autores principales: Zhang, Haojie, Chen, Yituo, Li, Feida, Wu, Chenyu, Cai, Wanta, Ye, Hantao, Su, Haohan, He, Mingjun, Yang, Liangliang, Wang, Xiangyang, Zhou, Kailiang, Ni, Wenfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825014/
https://www.ncbi.nlm.nih.gov/pubmed/36609266
http://dx.doi.org/10.1186/s12974-023-02690-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825014/
https://www.ncbi.nlm.nih.gov/pubmed/36609266
http://dx.doi.org/10.1186/s12974-023-02690-4

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