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The hepatic integrated stress response suppresses the somatotroph axis to control liver damage in nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) can be ameliorated by calorie restriction, which leads to the suppressed somatotroph axis. Paradoxically, the suppressed somatotroph axis is associated with patients with NAFLD and is correlated with the severity of fibrosis. How the somatotroph axis becomes...

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Detalles Bibliográficos
Autores principales: Ohkubo, Rika, Mu, Wei-Chieh, Wang, Chih-Ling, Song, Zehan, Barthez, Marine, Wang, Yifei, Mitchener, Nathaniel, Abdullayev, Rasul, Lee, Yeong Rim, Ma, Yuze, Curtin, Megan, Srinivasan, Suraj, Zhang, Xingjia, Yang, Fanghan, Sudmant, Peter H., Pisco, Angela Oliveira, Neff, Norma, Haynes, Cole M., Chen, Danica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825120/
https://www.ncbi.nlm.nih.gov/pubmed/36516757
http://dx.doi.org/10.1016/j.celrep.2022.111803