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A subclass of archaeal U8-tRNA sulfurases requires a [4Fe–4S] cluster for catalysis

Sulfuration of uridine 8, in bacterial and archaeal tRNAs, is catalyzed by enzymes formerly known as ThiI, but renamed here TtuI. Two different classes of TtuI proteins, which possess a PP-loop-containing pyrophosphatase domain that includes a conserved cysteine important for catalysis, have been id...

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Detalles Bibliográficos
Autores principales: He, Nisha, Zhou, Jingjing, Bimai, Ornella, Oltmanns, Jonathan, Ravanat, Jean-Luc, Velours, Christophe, Schünemann, Volker, Fontecave, Marc, Golinelli-Pimpaneau, Béatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825150/
https://www.ncbi.nlm.nih.gov/pubmed/36533440
http://dx.doi.org/10.1093/nar/gkac1156