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A subclass of archaeal U8-tRNA sulfurases requires a [4Fe–4S] cluster for catalysis
Sulfuration of uridine 8, in bacterial and archaeal tRNAs, is catalyzed by enzymes formerly known as ThiI, but renamed here TtuI. Two different classes of TtuI proteins, which possess a PP-loop-containing pyrophosphatase domain that includes a conserved cysteine important for catalysis, have been id...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825150/ https://www.ncbi.nlm.nih.gov/pubmed/36533440 http://dx.doi.org/10.1093/nar/gkac1156 |