PAM-independent ultra-specific activation of CRISPR-Cas12a via sticky-end dsDNA

Although CRISPR-Cas12a [clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein 12a] combining pre-amplification technology has the advantage of high sensitivity in biosensing, its generality and specificity are insufficient, which greatly restrains its applicati...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Mu, Yaoqin, Dong, Kejun, Zhang, Lei, Yan, Bei, Hu, Hao, Liao, Yangwei, Zhao, Rong, Shu, Wan, Ye, Zhengxin, Lu, Yaping, Wan, Chong, Sun, Qiangqiang, Li, Longjie, Wang, Hongbo, Xiao, Xianjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825152/
https://www.ncbi.nlm.nih.gov/pubmed/36484104
http://dx.doi.org/10.1093/nar/gkac1144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825152/
https://www.ncbi.nlm.nih.gov/pubmed/36484104
http://dx.doi.org/10.1093/nar/gkac1144

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