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Cdk1-mediated threonine phosphorylation of Sam68 modulates its RNA binding, alternative splicing activity and cellular functions

Sam68, also known as KHDRBS1, is a member of the STAR family of proteins that directly link signal transduction with post-transcriptional gene regulation. Sam68 controls the alternative splicing of many oncogenic proteins and its role is modulated by post-translational modifications, including serin...

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Detalles Bibliográficos
Autores principales: Malki, Idir, Liepina, Inara, Kogelnik, Nora, Watmuff, Hollie, Robinson, Sue, Lightfoot, Adam, Gonchar, Oksana, Bottrill, Andrew, Fry, Andrew M, Dominguez, Cyril
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825155/
https://www.ncbi.nlm.nih.gov/pubmed/36537190
http://dx.doi.org/10.1093/nar/gkac1181